Topical curcumin for HPV-related early cervical changes
Part of Cancer, Infections, Women’s health & pregnancy clinical trials.
This Phase 2 study tests whether a curcumin (a natural plant compound) cream/gel applied to the cervix can help treat cervical cell changes linked to HPV. It focuses on people with mild (LSIL) or recently treated severe (HSIL) precancer changes, aiming to reduce disease and improve healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a cervix and have HPV-related cervical changes: confirmed LSIL, or HSIL that was recently treated
- If your HSIL is the only condition, your LEEP procedure must be done within the last 6 weeks and healing must be going well
- If you have HIV, you must not have AIDS-related illness, and your viral load must be continuously undetectable for at least 3 months while on anti-HIV meds
- If you have HIV, your immune cells (CD4) must be above 200 cells/mL
- You must use reliable birth control (pill, long-acting option, tubal ligation, or Depo shot) and be willing to follow study visits
- You must have no signs that suggest invasive cancer or deeper microinvasion on exam/biopsy, and you must not be pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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