Tissue-engineered cornea transplant for specific eye swelling conditions
Part of Eyes & vision, Genetic & congenital clinical trials.
This Phase 1 trial tests a new, lab-made tissue transplant to improve corneal clarity in people with certain types of corneal endothelium failure (eye swelling) caused by specific conditions. The main goal is to check safety and see if vision and corneal health improve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Have mild to moderate corneal endothelial decompensation or bullous keratopathy, with minimal scarring in the cornea’s middle layer
- Your specific cause should be something like Fuchs’ endothelial dystrophy or a post-surgery corneal failure (bullous keratopathy) after cataract/other surgery
- You should not have severe or late-stage corneal scarring, or other complicated eye problems that would make this transplant technique unlikely to work
- Be between 21 and 80 years old, and not pregnant
- Be willing and able to participate, and not have a cognitive condition that prevents understanding/consent
- Have no known allergy to the antibiotics used in the trial
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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