High-dose vitamin D for kids with IBD on biologic therapy
Treatments studied
Part of Digestive system, Hormones & metabolism clinical trials.
This trial studies whether giving a higher dose of vitamin D3 helps children and teens with inflammatory bowel disease (Crohn’s or ulcerative colitis) who have low vitamin D levels. Participants are already on biologic medicines and will be treated while monitoring blood (and safety) related to vitamin D.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an existing diagnosis of Crohn disease, ulcerative colitis, or indeterminate colitis
- You are taking infliximab or vedolizumab on a schedule every 4–8 weeks
- Your age is 5 to 25 years old
- A recent blood test in the last 4–8 weeks shows low vitamin D (25-OHD under 40 ng/mL), and your vitamin D dose did not change since then
- You do not have known kidney disease or liver disease
- You can safely take vitamin D3 by mouth (as a pill), and you do not have a history of high calcium in the blood or urine
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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