GnRH shot before frozen embryo transfer for endometriosis
Treatments studied
Part of Women’s health & pregnancy clinical trials.
This trial studies whether giving a GnRH “downshifting” shot before transferring a frozen embryo can improve pregnancy outcomes for people with endometriosis or adenomyosis. It may help by changing hormone activity before the transfer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 to 35 (not under 18 or 36 and older)
- You have endometriosis and/or adenomyosis and a planned frozen embryo transfer of a blastocyst
- Your uterine cavity is normal (no major internal uterine blockages or growths)
- You had an MRI during screening that shows endometriosis and/or adenomyosis
- Your BMI is 35 or less
- You can safely take the study medicines (no certain allergies and key medical conditions)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether using a hormone medication (GnRH agonist) before a frozen embryo transfer helps women with adenomyosis. If you have adenomyosis and are planning a frozen embryo transfer, this trial will help compare results with or without the pre-treatment.
This study tests whether frozen embryo transfer (placing a previously frozen embryo in the uterus) is effective for women with adenomyosis (a condition where uterine tissue grows into the uterine wall). It may help improve pregnancy chances for women with this condition.
This study tests an experimental injection (HHK001) compared to a standard hormone-blocking medicine (Enantone) for women with endometriosis. The goal is to see if the new injection is safe, how it works in the body, and if it helps with endometriosis symptoms.
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