Minimally invasive lymph node treatment after chemo for node-positive breast cancer
Part of Cancer, Skin clinical trials.
This study looks at a less invasive way to check and treat lymph nodes in the armpit after you receive chemotherapy (and sometimes immunotherapy) before breast surgery. It may help people with cancer that has already spread to armpit lymph nodes by improving how staging and treatment are done.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have invasive breast cancer on one side (not both breasts).
- Before treatment, your armpit lymph nodes were thought to be involved (cN1 to cN3).
- You have confirmation that at least one armpit lymph node contains cancer (pathology proof).
- You plan to receive neoadjuvant chemotherapy (sometimes with immunotherapy) before surgery.
- You have not had prior armpit surgery or armpit radiation before starting this chemotherapy.
- You do not have cancer that has spread to distant parts of the body (no metastases, even limited/oligometastatic disease).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a treatment plan for early breast cancer that involves at least three suspicious lymph nodes on the ultrasound/imaging. It looks at whether a targeted technique—done before surgery with chemotherapy—can improve or guide care when surgery will remove the lymph nodes.
This study looks at the safest and most useful way to remove and check breast-cancer lymph nodes in the armpit after you finish chemotherapy given before surgery. It may help you avoid unnecessary surgery while still getting accurate information about how well the treatment worked.
This trial studies how doctors should operate on lymph nodes after you finish chemotherapy given before surgery. It may help improve treatment planning for people whose breast cancer has spread to nearby lymph nodes, but not to distant organs.
This study tests whether patients with advanced breast cancer (with lymph node involvement) who shrink their cancer with chemotherapy before surgery can safely skip complete lymph node removal and just have a smaller sentinel node procedure instead. The goal is to reduce surgery-related side effects while maintaining good cancer outcomes.
This trial tests whether it's safe to skip armpit surgery in people whose breast cancer has responded well to chemotherapy and whose lymph nodes appear cancer-free on ultrasound. It aims to reduce side effects like arm swelling while still controlling the cancer.
This study looks at whether some breast cancer patients can safely skip a surgery that removes lymph nodes in the armpit after their initial (pre-surgery) treatment shows the armpit is likely clear. It may reduce surgical side effects if the armpit truly responds well.
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.