Tests adding a targeted approach for breast cancer with many involved nodes
Part of Cancer, Skin clinical trials.
This trial studies a treatment plan for early breast cancer that involves at least three suspicious lymph nodes on the ultrasound/imaging. It looks at whether a targeted technique—done before surgery with chemotherapy—can improve or guide care when surgery will remove the lymph nodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your caregiver) sign a consent form and agree to follow study instructions
- You are age 18 or older, with a confirmed invasive breast cancer diagnosis from a core biopsy
- Your imaging shows clinically positive lymph nodes (cN+) with at least 3 suspicious lymph nodes, and at least one suspicious node was biopsied
- Before starting chemotherapy, the suspicious lymph node(s) are marked (for example with a clip or seed) so doctors can find the exact node(s) later
- You do not have distant metastases (cancer spread to far organs), and you must be planned to receive chemotherapy as part of treatment
- You must be able to have the planned surgery that includes both the targeted approach (TAD) and axillary lymph node dissection (ALND), with at least 7 lymph nodes removed for lab testing
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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