Less lymph node surgery after chemotherapy for breast cancer
Part of Cancer, Skin clinical trials.
This study looks at whether it's safe to do less extensive lymph node surgery (removing only the sentinel node instead of all lymph nodes) for breast cancer that has spread to lymph nodes, after chemotherapy has shrunk the cancer. The goal is to reduce side effects while still effectively treating the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have a type of breast cancer that has spread to lymph nodes (stages T1-3, N2-3) at diagnosis, before chemotherapy.
- You have completed all planned neoadjuvant chemotherapy before surgery. (Chemotherapy after surgery is not allowed, though other treatments after surgery are okay.)
- Your doctor confirmed cancer in your lymph nodes with a needle biopsy before or during the first two weeks of chemotherapy.
- You have had a sentinel node biopsy (where the surgeon finds the first lymph node that cancer would spread to) as part of your surgery, and at least one sentinel node was found.
- You have a good performance status (able to do daily activities) and are considered medically fit for surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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