Clin2
NCT04671511Possibly a fitRecruiting

Check targeted lymph node surgery for early breast cancer

Breast Cancer FemaleEarly-stage Breast CancerLymph Node MetastasesAxillary MetastasesSentinel Lymph Node

Part of Cancer, Skin clinical trials.

This study tests a more focused surgery approach to remove lymph nodes in the armpit for people with early breast cancer that has been found in 1–2 axillary lymph nodes. It may help guide more precise treatment while checking how well this approach works.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
98 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You have early invasive breast cancer in the breast (T1 or T2 type), and it can be any hormone or HER2 subtype.
  • On exam, your armpit lymph nodes feel normal (N0) but ultrasound shows up to two suspicious nodes, and biopsy confirms cancer in the armpit node(s).
  • Your overall health/mobility score must be less than 2 (you can do daily activities with limited trouble).
  • You must sign a study consent form after understanding it.
  • You should not have had prior surgery in the same armpit area, prior axillary (armpit) radiation, distant spread (metastases), or chemotherapy before surgery (neoadjuvant therapy).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05763641Recruiting
Targeted treatment after chemo for certain breast cancers

This trial studies an additional treatment given after chemotherapy for locally advanced breast cancer that has spread to specific underarm lymph nodes. It may help some people reduce cancer returning, especially when tumors match certain growth and spread features.

L'Hospitalet de Llobregat, Barcelona
NCT05935150Recruiting
Skipping lymph node surgery in early breast cancer

This trial studies whether you can safely avoid a lymph node biopsy in the armpit for early breast cancer when scans and exams look negative. It may reduce surgery-related side effects while still keeping cancer care on track.

Nanjing, Jiangsu
NCT04109079Recruiting
Best surgery plan for breast cancer lymph nodes after chemotherapy

This study looks at the safest and most useful way to remove and check breast-cancer lymph nodes in the armpit after you finish chemotherapy given before surgery. It may help you avoid unnecessary surgery while still getting accurate information about how well the treatment worked.

Dublin
NCT07085442Recruiting
Targeted biopsy for breast cancer that has spread to lymph nodes

This study reviews patients with early breast cancer that has spread to a small number of lymph nodes. It looks at how well a special biopsy removes those nodes during surgery, to help guide future care.

Burnley
NCT04889924Recruiting
Lymph node surgery vs radiation after chemo for breast cancer

This trial compares two ways to treat the underarm lymph nodes in people whose sentinel lymph node still shows limited cancer after chemotherapy and hormone treatment. It may help find which approach controls cancer better with fewer side effects.

Sydney, New South Wales
NCT04744506Recruiting
Targeted removal of armpit nodes after chemotherapy for breast cancer

This trial studies a more targeted surgery to remove cancer-involved lymph nodes in the armpit after you finish chemotherapy before surgery. It may help doctors better remove affected nodes while avoiding unnecessary tissue removal.

Hangzhou, Zhejiang

Hear when a new Breast Cancer Female trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.