Clin2
NCT04889924Possibly a fitRecruiting

Lymph node surgery vs radiation after chemo for breast cancer

Breast CancerChemotherapySentinel Lymph NodeAxillary Lymph Nodes DissectionRadiotherapy Side Effect

Part of Cancer, Injuries & trauma, Skin clinical trials.

This trial compares two ways to treat the underarm lymph nodes in people whose sentinel lymph node still shows limited cancer after chemotherapy and hormone treatment. It may help find which approach controls cancer better with fewer side effects.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
820 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You had breast cancer with no or limited lymph node spread at the start (N0, or N1) and you later had neoadjuvant (pre-surgery) therapy
  • After neoadjuvant treatment, your sentinel (first) underarm lymph node still has no more than 2 small or larger cancer spots (macrometastasis or micrometastasis), or only tiny “ITCs” spots
  • After treatment, ultrasound or MRI shows an acceptable response in the underarm area
  • You finished at least 70% of your chemotherapy, and completed about 6 months of hormone (endocrine) treatment
  • You have not had lymph node or breast surgery on the same breast for cancer within the last 10 years

View the official record on ClinicalTrials.gov

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Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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