Chemo before surgery versus surgery first for stomach cancer
Part of Cancer, Digestive system clinical trials.
This trial compares giving chemotherapy before surgery versus going straight to surgery in older adults with stage III stomach (or where the esophagus meets the stomach) cancer. It’s meant to see which approach works better to control the cancer and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed stomach cancer (adenocarcinoma) or cancer at the esophagogastric junction, and it is not blocking food flow
- Your cancer is stage III based on scans and exam (clinically stage III)
- You are able to do daily activities reasonably well: you’re usually up and moving more than half the day (ECOG 0–2)
- You must be healthy enough for both chemotherapy and stomach cancer surgery, including adequate kidney, liver, blood counts, and lung function
- You have not had chemotherapy or radiation before, and you are not in another study
- There is no spread to distant organs (no distant metastases), and the cancer is not considered inoperable
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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