BMAC injection for severe knee osteoarthritis before knee surgery
Treatments studied
Part of Bones, joints & muscles clinical trials.
This trial studies injecting “bone marrow aspirate concentrate” (BMAC) into the knee to help relieve pain from severe knee osteoarthritis. It’s for people who have strong signs of advanced arthritis on X-ray and still have ongoing pain despite usual treatments, before a planned knee procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 45 and 75 years old
- Your knee X-rays show severe arthritis (Kellgren-Lawrence grade IV)
- Your doctor (primary care or orthopedist) says you need a total knee arthroscopy
- You have ongoing knee pain that hasn’t improved with standard treatments like pain medicines, physical therapy, or joint injections
- You’ve tried treatments such as acetaminophen, anti-inflammatory medicines, steroid or hyaluronic acid injections
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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