Ketamine to help prevent repeat suicide attempts in youth
Treatments studied
Part of Mental health clinical trials.
This Phase 3 study tests ketamine to reduce ongoing suicidal thoughts and help prevent another suicide attempt in youth after a recent attempt. It will compare ketamine treatment against standard care to see if it helps improve safety and reduce suicide risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 14 and 30 years old
- Have been admitted to a specific hospital after a non-fatal suicide attempt and still have suicidal thoughts
- Have a suicidal thoughts score of 6 or higher on a clinician-rated questionnaire
- Be able to understand and sign written consent (patient and/or legal process as applicable)
- Must not have certain mental health diagnoses or major breathing/heart/medication risks that make ketamine unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a medicine called ketamine (given as a shot under the skin) to see if it helps reduce depression and suicidal thoughts in teenagers. It is for teens aged 12 to 19 who are already getting treatment for depression but still have serious suicidal thoughts or have attempted suicide.
This study tests whether ketamine can help reduce suicidal thoughts in people with depression. It also looks at how ketamine affects a brain receptor that may be linked to mood and stress, to learn why it might help.
This trial tests if a single dose of ketamine can quickly reduce suicidal thoughts in people who come to the emergency department. If you are having active suicidal thoughts and need inpatient care, you may be able to join.
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
This Phase 4 study tests whether ongoing treatment with ketamine or esketamine can reduce suicidal thoughts in people with major depression who are at high risk. Because the study focuses on long-term maintenance, you’d receive treatment over time while being closely monitored for safety and mental health changes.
This study tests whether ketamine plus a structured crisis-response plan can help reduce suicidal thoughts for adults admitted from the ER. It also aims to make care in the emergency setting more consistent and effective.
Hear when a new Suicide, Attempted trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.