Ketamine maintenance to help prevent suicidal thoughts
Treatments studied
Part of Mental health clinical trials.
This Phase 4 study tests whether ongoing treatment with ketamine or esketamine can reduce suicidal thoughts in people with major depression who are at high risk. Because the study focuses on long-term maintenance, you’d receive treatment over time while being closely monitored for safety and mental health changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are currently an inpatient in a psychiatric unit (or you’re waiting to be transferred to psychiatry).
- You are age 18 to 70 and have been diagnosed with major depressive disorder (MDD) with a current severe depressive episode lasting at least 8 weeks.
- You have recent suicidal thoughts or behaviors leading to your hospital admission, with a specific suicidal-thought score during screening.
- You can have study safety checks (physical exam, labs, and ECG if needed) and you don’t have unstable or unsafe medical conditions.
- If you could become pregnant, you must use an approved birth-control method during the whole study and have a negative pregnancy test at screening.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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