Clin2
NCT04768426Possibly a fitRecruiting

Watching DNA in blood while taking capecitabine after breast cancer

Triple Negative Breast CancerBreast Cancer

Treatments studied

Part of Cancer, Skin clinical trials.

This trial checks how a blood test that looks for cancer DNA (ctDNA) changes during and after you take capecitabine after early triple-negative breast cancer. It aims to see whether these blood test results can help monitor the chance of the cancer coming back.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You had stage I to III triple-negative breast cancer when diagnosed, with ER and PR less than 10%
  • Your cancer was still there after at least 4 cycles of chemo before surgery (neoadjuvant chemo)
  • You are 18 or older, and your day-to-day functioning is fairly good (ECOG 0 to 2)
  • Your scans/tests show no spread to distant organs (no metastatic disease)
  • You’re planning 6 months or 8 cycles of capecitabine as post-surgery treatment
  • You can take pills by mouth and all major side effects from prior treatment are mostly gone (back to grade 0–1, except hair loss and certain nerve issues)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04803539Recruiting· Phase 2/Phase 3
ctDNA-guided booster treatment after chemo for triple-negative breast cancer

This trial uses a blood test called ctDNA to see who is at higher risk after surgery and standard chemotherapy for triple-negative breast cancer. If your ctDNA test is positive, you may receive an extra “boost” treatment to help reduce the chance the cancer returns.

Guandong, Guangdong
NCT06787339Not yet recruiting· Phase 2
Capecitabine for low-risk triple negative breast cancer

This trial tests whether a chemotherapy pill called capecitabine can help people with low-risk triple negative breast cancer after surgery. It is for patients with stage I disease who have certain features that suggest a lower chance of recurrence.

Shanghai, Shanghai Municipality
NCT04501523Recruiting· Phase 2
ctDNA-guided immunotherapy boost after chemotherapy for triple-negative breast cancer

This Phase 2 study checks whether a blood test that looks for cancer DNA (ctDNA) can help decide who should get an extra 12-month immunotherapy treatment after standard chemotherapy and surgery. It may help reduce the chance of the cancer coming back in people with triple-negative breast cancer.

Guandong, Guangdong
NCT04353557Recruiting
Blood test monitoring in early-stage breast cancer

This trial uses a special blood test to track cancer signals (called ctDNA) during and after treatment for early breast cancer. It aims to see whether monitoring these signals can help guide follow-up and treatment decisions.

Chongqing, Chongqing Municipality
NCT07478705Not yet recruiting
Detecting breast cancer return early with a blood test and scans

This trial uses a simple blood test (liquid biopsy) and imaging to look for early signs that triple-negative breast cancer has returned after treatment. It is for people who had stage II or III cancer, went through chemotherapy before surgery, and still had cancer left after surgery.

NCT03357120Recruiting
Using blood DNA to assess response after breast cancer chemotherapy

This study checks whether a blood test that looks for “tumor DNA” (circulating tumor DNA) can help evaluate how well neoadjuvant chemotherapy worked for breast cancer. It may help doctors better understand treatment response after surgery.

Bordeaux

Hear when a new Triple Negative Breast Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.