Testing a new heart procedure for severe leaking mitral valve
Part of Heart & circulation clinical trials.
This trial studies a new transcatheter (through the heart without open surgery) mitral valve treatment for people with severe mitral valve leaking who are too high-risk for standard surgery. It may help reduce valve leakage and improve symptoms, but it’s an early “first-in-human” device study.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re at least 60 years old.
- You have severe mitral valve regurgitation (mitral valve leaking) with symptoms.
- A heart team says you’re not eligible for standard mitral surgery and not eligible for other transcatheter mitral repair options.
- Your heart pumping strength is reduced, but your ejection fraction is at least 30%.
- You have symptoms that fit NYHA class III or IV (breathless or limited with less activity).
- You can and will sign consent, follow the study plan, and you’re not planning to move abroad.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether a new catheter-based system can replace a badly leaking mitral valve in people who have symptoms. It may help if you can’t safely get current approved valve treatments or standard surgery.
This trial studies an “epicardial” device placed during planned heart surgery to reduce mitral valve leaking (“mitral regurgitation”). If you have moderate-to-severe valve leak from ischemic heart disease and are already scheduled for heart surgery, this may help improve how well the valve works.
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
This trial tests a new device designed to fix a leaky mitral valve in people with heart failure. It may help you breathe easier and feel less tired if your valve leak is severe and medicines have not been enough.
This trial tests a new device called AMEND™ that is placed through a vein in the leg to repair a leaky mitral valve without open-heart surgery. It is for people with significant mitral regurgitation who are at high risk for surgery.
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
Hear when a new Mitral Valve Regurgitation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.