Testing a new catheter procedure to replace a leaking mitral valve
Part of Heart & circulation clinical trials.
This trial studies whether a new catheter-based system can replace a badly leaking mitral valve in people who have symptoms. It may help if you can’t safely get current approved valve treatments or standard surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate-to-severe or severe mitral valve leakage causing symptoms
- Your heart team decides you are not suitable for approved catheter repair or usual mitral valve procedures
- You have not had a previous mitral valve replacement or repair using a catheter device that is still in place
- Your heart’s pumping strength (left ventricular ejection fraction) is at least 25%
- Your heart valve/heart structure has no major anatomic problems that block the procedure
- You are not too unstable and do not need urgent or emergency surgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies a new way to replace a damaged mitral heart valve using a catheter (a thin tube), instead of open-heart surgery. It may help people who have severe leaking of the mitral valve but are considered too high-risk for surgery.
This trial tests a new device called the Medtronic Intrepid TTVR system to replace the tricuspid valve in people with severe tricuspid regurgitation (leaky valve). It aims to see if the device can safely and effectively fix the leak and improve symptoms.
This trial studies a catheter-based procedure to replace the mitral valve in people with severe (or specific moderate) mitral valve leakage that causes symptoms. It may help by reducing leaking and related symptoms when standard surgery or less invasive fixes aren’t suitable for you.
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