Sentinel node biopsy versus full node removal in early uterine cancer
Part of Cancer, Women’s health & pregnancy clinical trials.
This study compares two ways to check lymph nodes during surgery for early-stage endometrial (uterine) cancer: sentinel node biopsy versus removing more lymph nodes. It may help find whether the less extensive approach can stage the cancer accurately with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman age 20 to 80
- You have newly diagnosed endometrial cancer and have never had cancer treatment before
- Your cancer type and grade fit specific categories (endometrioid, serous, clear cell, and others; FIGO grades 1–3)
- Your cancer is expected to be early stage I–II (not stage III–IV)
- Your biggest lymph node is small (15 mm or less) on an MRI, and you are planned for laparoscopic or robotic hysterectomy with lymph node removal
- You can have required blood tests and generally are well enough for surgery (ECOG 0–2 and ASA 0–2), and you can sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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