Sentinel node biopsy versus full node removal in early uterine cancer
Part of Cancer, Women’s health & pregnancy clinical trials.
This study compares two ways to check lymph nodes during surgery for early-stage endometrial (uterine) cancer: sentinel node biopsy versus removing more lymph nodes. It may help find whether the less extensive approach can stage the cancer accurately with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman age 20 to 80
- You have newly diagnosed endometrial cancer and have never had cancer treatment before
- Your cancer type and grade fit specific categories (endometrioid, serous, clear cell, and others; FIGO grades 1–3)
- Your cancer is expected to be early stage I–II (not stage III–IV)
- Your biggest lymph node is small (15 mm or less) on an MRI, and you are planned for laparoscopic or robotic hysterectomy with lymph node removal
- You can have required blood tests and generally are well enough for surgery (ECOG 0–2 and ASA 0–2), and you can sign consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two ways to remove lymph nodes during hysterectomy for endometrial cancer that hasn't spread. The goal is to find which method works better with similar or fewer side effects.
This trial tests whether removing only the first lymph node to detect cancer spread (sentinel node mapping) is as effective as removing all lymph nodes in the pelvic area (comprehensive lymphadenectomy) for a specific type of endometrial cancer with a p53 mutation, stages I–II. The goal is to see if the less extensive surgery can result in similar outcomes while possibly reducing side effects.
This trial studies how to find the “sentinel” (first) lymph node during surgery for high-risk endometrial (uterine) cancer. It may help surgeons better tell whether cancer has spread to nearby lymph nodes and guide the extent of lymph node removal.
This trial compares two ways of removing lymph nodes during a vaginal minimally invasive surgery for early-stage endometrial cancer. It aims to find which method is safer and more effective.
This study compares two minimally invasive surgical techniques for women with early-stage endometrial cancer who need lymph node sampling during their cancer surgery. Both approaches are designed to check if cancer has spread to lymph nodes while causing less trauma to the body than traditional open surgery.
This trial tests a new way to look at lymph nodes during surgery for gynecologic cancers. It may help doctors decide immediately if cancer has spread to the lymph nodes, which could guide treatment decisions during the same operation.
Hear when a new Endometrial Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.