Clin2
NCT06677112Possibly a fitRecruiting

Comparing lymph node removal methods for endometrial cancer

Endometrial Cancer

Part of Cancer, Women’s health & pregnancy clinical trials.

This trial compares two ways to remove lymph nodes during hysterectomy for endometrial cancer that hasn't spread. The goal is to find which method works better with similar or fewer side effects.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
625 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You need to be scheduled for a complete hysterectomy that includes removal of both ovaries and fallopian tubes, with lymph node removal.
  • You must have endometrial cancer confirmed by biopsy that is still only in the uterus.
  • Your cancer should have no signs of having spread beyond the uterus on pre-surgery scans.
  • If you had chemotherapy before, it must be at least 5 years ago and you must show no signs of cancer now.
  • You must have a life expectancy of at least 6 months and have normal liver function tests.
  • You cannot have had prior radiation to the pelvis, abdomen, or vagina, or previous lymph node removal in the pelvis.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06870903Recruiting
Comparing two lymph node removal methods in vaginal surgery for early endometrial cancer

This trial compares two ways of removing lymph nodes during a vaginal minimally invasive surgery for early-stage endometrial cancer. It aims to find which method is safer and more effective.

Diyarbakır, Baglar
NCT04845828Recruiting
Sentinel node biopsy versus full node removal in early uterine cancer

This study compares two ways to check lymph nodes during surgery for early-stage endometrial (uterine) cancer: sentinel node biopsy versus removing more lymph nodes. It may help find whether the less extensive approach can stage the cancer accurately with fewer side effects.

Seoul
NCT06900582Not yet recruiting
Comparing lymph node removal methods for p53-mutated uterine cancer

This study compares two ways of removing lymph nodes during surgery for a high-risk type of uterine (endometrial) cancer with a p53 gene mutation. You would be randomly assigned to either removing only the sentinel (first few) lymph nodes or removing many lymph nodes, to see if the less invasive approach is just as good.

NCT04504006Recruiting
Tracking surgery choices for lymph node spread in endometrial cancer

This is an observational study that follows people with endometrial cancer who have had surgery to check and remove pelvic (and sometimes paraaortic) lymph nodes. It looks at how different surgical approaches and any added treatment affect local control (keeping cancer from coming back in the pelvis/nearby areas).

Essen, North Rhine-Westphalia
NCT07583329Not yet recruiting
Comparing two minimally invasive surgeries for endometrial cancer

This study compares two minimally invasive surgery methods for endometrial cancer: traditional laparoscopy (small cuts in the belly) and vNOTES (surgery through the vagina). Both use a sentinel lymph node biopsy to check if cancer has spread, and the goal is to see which approach works better.

Adana
NCT06935305Recruiting
Testing a faster method to find cancer in sentinel lymph nodes

This trial compares a fast lab test (OSNA) with standard microscope checks to see which better finds cancer in the first lymph node (sentinel node) during surgery for early-stage endometrial cancer. It aims to improve accuracy and speed while avoiding unnecessary lymph node removal.

Rome, Italy

Hear when a new Endometrial Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.