Comparing lymph node removal methods for p53-mutated uterine cancer
Part of Cancer, Women’s health & pregnancy clinical trials.
This study compares two ways of removing lymph nodes during surgery for a high-risk type of uterine (endometrial) cancer with a p53 gene mutation. You would be randomly assigned to either removing only the sentinel (first few) lymph nodes or removing many lymph nodes, to see if the less invasive approach is just as good.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your cancer is a high-risk type that has a p53 gene mutation.
- Your cancer has not spread far, only to the cervix or ovary, and not to lymph nodes.
- You have a negative PET-CT scan, meaning no lymph node involvement, within 2 months before surgery.
- You are healthy enough for surgery and anesthesia, with an ECOG performance status of 0-1.
- You have not had prior chemotherapy, radiation, or hormone therapy for this cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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