Laparoscopic versus open ALPPS to regrow liver before surgery
Part of Cancer, Digestive system clinical trials.
This study compares two ways of doing a staged liver surgery (ALPPS) to help regrow enough liver for people with certain liver cancers. It looks at outcomes and how well the remaining liver grows after surgery, using different surgical approaches.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have liver cancer and are planning an extended right liver surgery (right hepatectomy or right trisectionectomy)
- You are at least 18 years old and can give informed consent
- Your “future liver remnant” is small: it must be 30% or less, and a dye test must be below a set level (ICG clearance at 15 minutes < 18%)
- Your liver function fits Child-Pugh Class A (mildest cirrhosis) and your anesthesia risk is low (ASA score < 3)
- Your energy level is good enough (ECOG score 0–2) and platelets are above 100 (units as reported by your clinic)
- You should not have severe liver complications like fluid buildup (ascites), bleeding from veins (varices), or confusion from liver disease (hepatic encephalopathy)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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