Clin2
NCT04877093Possibly a fitRecruiting

Low-dose clonidine for PTSD nightmares in veterans

PTSDPosttraumatic Stress DisorderSleep

Part of Mental health clinical trials.

This Phase 3 study tests whether low-dose clonidine can reduce PTSD symptoms and especially nightmares in U.S. veterans. You’d be screened for PTSD severity and current treatments, then asked to visit the clinic as scheduled to see if the treatment helps.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
32 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Be at least 18 years old and a U.S. military veteran
  • Have a current PTSD diagnosis confirmed by a clinician
  • Score high enough on PTSD questionnaires and nightmare-related items
  • Speak and understand English and agree to attend clinic visits as planned
  • Not be pregnant or breastfeeding
  • Not have certain heart/blood pressure problems or medication conflicts

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07664631Not yet recruiting· Phase 1
Testing stimulant medications for PTSD

This study tests whether stimulant medications can help treat PTSD symptoms. Researchers want to see if these medications are safe and effective for people with PTSD.

Chicago, Illinois
NCT04452500Recruiting· Phase 2
Study drug for PTSD symptoms in Veterans

This trial tests a study medicine that blocks the effects of cortisol (a stress hormone) to reduce PTSD symptoms in Veterans. It’s meant for people with ongoing PTSD symptoms and stable treatments, and it closely checks safety because the medicine can affect sleep, mood, and heart rhythm.

Tuscaloosa, Alabama
NCT06788522Not yet recruiting· Phase 4
Testing a sleep medication to help with PTSD

This study tests if a medication that blocks a brain chemical called orexin can help people with PTSD sleep better and reduce fear. You must have chronic PTSD, trouble sleeping, and be a U.S. military veteran.

San Francisco, California
NCT06577636Recruiting· Phase 2
Dream induction with anesthesia for PTSD

This trial tests whether inducing dreams during light anesthesia can help treat post-traumatic stress disorder (PTSD). You'll have a low-risk procedure where doctors monitor your brain activity and guide dreams to reduce PTSD symptoms.

Stanford, California
NCT07288593Not yet recruiting
Insomnia and Nightmare Study for Military Members

This study is testing a new approach to help military members and veterans who have trouble sleeping, including nightmares or a racing heart at night. It may be a good fit if you have insomnia and are not currently taking sleep medications.

Bethesda, Maryland
NCT05516277Recruiting
Insomnia care study for older adults with PTSD

This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).

North Hills, California

Hear when a new Posttraumatic Stress Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.