Clinical trials
Posttraumatic Stress Disorder clinical trials
Below are recruiting posttraumatic stress disorder clinical trials, each written for real people, not researchers. We’re tracking 108 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05527509Recruiting
Study of risk and resilience in new RCMP cadets
This study follows people as they start RCMP Cadet Training to learn what factors affect “risk” and “resilience” (how well someone adapts under stress). It may help improve support for cadets during training.
Regina, SaskatchewanAges 19–57 - NCT07840417Recruiting
Deep brain reorienting therapy for PTSD in veterans
This study tests a new type of talk therapy called deep brain reorienting (DBR) for veterans with post-traumatic stress disorder (PTSD). It aims to help your brain process traumatic memories and reduce PTSD symptoms over 8 sessions.
Edmonton, AlbertaAges 18–65 - NCT07756723RecruitingPhase 2/Phase 3
Comparing PTSD treatments for veterans with substance use
This study compares two proven treatments for veterans who have both PTSD and substance use problems. It aims to find which treatment works best to help with trauma recovery.
Coatesville, PennsylvaniaAges 18 years+ - NCT07707765Recruiting
Early help after sepsis in the ICU to prevent PTSD
This study tests whether early psychological support after sepsis in the ICU can reduce the chance of developing posttraumatic stress disorder (PTSD). If you recently left the ICU after sepsis, you may be able to join.
AshkelonAges 18–120 - NCT05961306Recruiting
Testing a stepped screening plan during pregnancy and after birth
This study checks how well a step-by-step screening approach and its tools work for identifying issues during pregnancy (weeks 20–24) or in early postpartum (6–10 weeks after delivery). It may help doctors use more accurate screening to decide who needs further care.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07604753Recruiting
Comparing two mental health screening questionnaires
This study compares two different questionnaires that doctors use to diagnose mental health conditions. Researchers want to check if a newer, shorter questionnaire works just as well as the longer standard one.
Hong KongAges 18 years+ - NCT07483333Recruiting
Comparing two group therapies for kids with medical conditions and trauma
This study compares two types of group therapy for youth ages 8–18 who have a chronic medical condition and trauma-related distress. The goal is to see which type of group helps kids feel better and handle their health challenges.
Chicago, IllinoisAges 8–18 - NCT07382323Recruiting
Comparing two talk therapies for anxiety and PTSD
This trial tests two types of therapy — metacognitive therapy and cognitive-behavioral therapy — to see which works better for people with certain anxiety disorders or PTSD. You would be randomly assigned to one of the treatments and attend regular sessions.
StockholmAges 18 years+ - NCT07306689Recruiting
PTSD after ectopic pregnancy
This study looks at whether people who have had an ectopic pregnancy (a pregnancy outside the womb) might experience posttraumatic stress disorder (PTSD). It aims to understand emotional impacts and may help improve care.
KrakowAges 18–45 - NCT07306676Recruiting
PTSD after early miscarriage
This study looks at post-traumatic stress after a miscarriage that happens early in pregnancy (up to 14 weeks). It aims to understand how people feel emotionally and mentally after this experience.
Krakow, MalopolskaAges 18–45 - NCT05663151Recruiting
Testing how prolonged exposure helps veterans with PTSD
This study looks at why a therapy called prolonged exposure (PE) helps people with PTSD. It includes veterans who want to start PE and checks certain safety and health factors to make sure PE can be used safely.
Boston, MassachusettsAges 18–90 - NCT07146633Recruiting
Testing an EMDR app for PTSD and substance use
This study tests an app that uses EMDR therapy to help people with both PTSD and substance use problems. EMDR is a type of therapy that uses eye movements or taps to help process traumatic memories. You would use the app at home and avoid starting other new therapies during the study.
Toronto, OntarioAges 18 years+ - NCT07106593Recruiting
Talk therapy for PTSD and tinnitus after concussion
This study tests a type of talk therapy for people with both PTSD and chronic tinnitus that started after a mild head injury. The therapy aims to help reduce symptoms of both conditions together.
San Antonio, TexasAges 18 years+ - NCT07060144Recruiting
CPT therapy for PTSD during pregnancy
This trial tests if Cognitive Processing Therapy (CPT), a type of talk therapy, can help pregnant women with PTSD. It aims to reduce PTSD symptoms and improve well-being.
Austin, TexasAges 18–46 - NCT06989957RecruitingPhase 1
Psilocybin and MDMA therapy for PTSD in veterans
This study tests whether a combination of two investigational drugs, psilocybin and MDMA, can help veterans with post-traumatic stress disorder (PTSD). You would receive the drugs in a controlled setting and be monitored closely.
Baltimore, MarylandAges 21 years+ - NCT06968832Recruiting
Prolonged therapy for PTSD and substance use
This trial tests a therapy that helps people with both post-traumatic stress disorder (PTSD) and a substance use disorder (SUD). You'll receive extended therapy sessions to reduce PTSD symptoms and support your recovery from substance use, while continuing your current substance use treatment.
Jacksonville, FloridaAges 18 years+ - NCT06947538Recruiting
Stepped care for PTSD: a study at Boston Medical Center
This study tests a step-by-step approach to treat posttraumatic stress disorder (PTSD). It aims to help you feel better by offering different treatment options based on your needs.
Boston, MassachusettsAges 18 years+ - NCT06937892Recruiting
Metacognitive therapy vs. Cognitive therapy for anxiety
This study compares two different types of therapy for anxiety disorders: metacognitive therapy (which focuses on how you think about your thoughts) versus cognitive-behavioral therapy (which works on changing thoughts and behaviors). It may help you find which approach works best for you.
StockholmAges 18 years+ - NCT06923423Recruiting
Cognitive processing therapy for drug use and trauma in prison
This study tests if a type of therapy called cognitive processing therapy (CPT) can help people in prison who have both a drug use problem and trauma-related stress. If you qualify, you would receive CPT and be compared to those getting usual care.
Little Rock, ArkansasAges 18 years+ - NCT06804525Recruiting
Adapting a mental health survey in Hong Kong
This study adapts a mental health survey for Hong Kong adults. It is open to adults aged 25 and older who live in randomly selected households and can speak Chinese or English.
Hong KongAges 25 years+ - NCT03642028RecruitingPhase 4
Sleep medicine study for PTSD-related sleep problems
This trial tests suvorexant, a sleep medicine, to help improve sleep disturbance in people with PTSD. It’s designed for adults who have had PTSD symptoms for at least a few months and also have insomnia.
Long Beach, CaliforniaAges 18–75 - NCT05701111Recruiting
School-based treatment for teens with trauma symptoms
This study tests a school-based approach to help teens who have experienced trauma and now have post-trauma symptoms. It also collects emotional and physical (biologic) information to understand how treatment may help.
Palo Alto, CaliforniaAges 11–17 - NCT06746818Enrolling by invitation
Building resilience in older adults with PTSD
This trial tests if a HeartMath-based program can help older adults improve resilience, reduce posttraumatic stress, and boost spiritual and psychosocial well-being. It may be an option if you are 60 or older and have experienced trauma.
Al MansurahAges 60 years+ - NCT06740487Recruiting
AR therapy for PTSD in military members
This study tests a new therapy using augmented reality (a type of headset that adds digital images to what you see) to help treat posttraumatic stress disorder (PTSD) in current or former military members. The therapy aims to make exposure therapy more effective by letting you face trauma-related situations in a controlled, virtual way.
Charleston, South CarolinaAges 18 years+
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Posttraumatic Stress Disorder trials by city
Studies with a site in or near these metro areas.
Posttraumatic Stress Disorder trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for posttraumatic stress disorder?
- Yes. Clin2 currently lists 108 recruiting posttraumatic stress disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a posttraumatic stress disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a posttraumatic stress disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.