Armpit radiation vs more surgery for early breast cancer with node spread
Part of Cancer, Skin clinical trials.
This trial tests whether radiation to the lower armpit (level I-II axilla) works as well as more extensive surgery for women with early-stage breast cancer that has spread to one or two sentinel lymph nodes (with cancer size > 2 mm). It aims to find a gentler treatment that still keeps the cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older with a new breast cancer diagnosis.
- The cancer has not spread to lymph nodes or other body parts (stages T1-3N0M0).
- You had breast-conserving surgery or mastectomy (with negative margins) as your first treatment.
- Sentinel lymph node biopsy found 1 or 2 spots of cancer larger than 2 mm (macrometastases), and you did not have further lymph node removal.
- You must be able to start radiation therapy within 12 weeks after your last chemo or surgery.
- You are willing to follow the treatment plan (surgeries, medications, and radiotherapy).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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