Sirolimus drug balloon for forked coronary artery blockages
Part of Heart & circulation clinical trials.
This trial studies a sirolimus drug-coated balloon to treat certain “forked” coronary artery blockages (bifurcation lesions). It aims to reduce re-narrowing of the artery and improve blood flow after the procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 18 to 85 (all sexes included).
- You have evidence of reduced blood flow to the heart (myocardial ischemia).
- Your angiogram shows a new (de novo) forked blockage where the side branch is narrowed at least 70%.
- After initial treatment, the side branch narrowing must be 50% or less with normal blood flow (TIMI grade 3).
- You must be able to have close follow-up visits and an angiogram at about 9 months.
- The artery size being treated must be about 2.0 to 4.0 mm wide, and the lesion should match the trial’s preferred balloon/stent approach.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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