Vagus nerve stimulation for nausea from chemo
Part of Cancer, Skin clinical trials.
This trial tests a non-invasive device that stimulates a nerve in your ear to help prevent nausea caused by chemotherapy. It is for people with breast cancer who are about to start a specific type of chemo (anthracycline and cyclophosphamide).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have breast cancer and are scheduled for anthracycline and cyclophosphamide chemotherapy.
- You have not had nausea or vomiting in the last 24 hours before the study starts.
- You have not taken any anti-nausea medication in the last 72 hours.
- You have not had chemotherapy before.
- You do not have any heart rhythm problems, severe heart failure, or a history of blood clots.
- You are able to use the ear stimulation device (your left ear must have a typical shape and no skin issues).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether stimulating the vagus nerve (a major nerve in your neck) can reduce joint and muscle pain caused by aromatase inhibitor medications used to treat breast cancer. Some patients may also receive immune-boosting cells to enhance pain relief.
This trial tests if a gentle nerve stimulation device on the ear can improve quality of life for people with ovarian cancer who are starting their first chemotherapy. It may help manage symptoms like fatigue or feeling sick.
This trial tests adding a simple ear-point stimulation to standard anti-nausea medicine for women receiving chemotherapy after breast cancer surgery. The goal is to see if this combination works better to prevent nausea and vomiting caused by the chemo drugs docetaxel and cyclophosphamide.
This trial tests whether stimulating specific points on your ear, combined with a steroid medication, can reduce nausea and vomiting caused by chemotherapy drugs (docetaxel and cyclophosphamide) given after breast cancer surgery. Many patients experience these side effects, and the study wants to see if this non-drug approach helps.
This trial tests whether stimulating specific points on your ear combined with a steroid medication can reduce nausea and vomiting caused by trastuzumab deruxtecan, a breast cancer drug. The goal is to help you feel better during treatment.
This trial tests a small device you wear on your ear to see if it can reduce nerve pain caused by chemotherapy (CIPN). You use it yourself at home, and it may help with the tingling, numbness, or burning in your hands and feet.
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.