Nerve stimulation for pain from breast cancer hormone therapy
Part of Cancer, Skin clinical trials.
This trial tests whether a gentle nerve stimulation treatment (called vagus nerve stimulation) can ease joint and muscle pain caused by aromatase inhibitors, which are common hormone therapy drugs for breast cancer. It may also test a type of immune cell therapy (IL-2) for people who do not get enough relief from the nerve stimulation alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult woman (18 or older).
- You have stage I, II, or III breast cancer that has not spread to distant organs.
- You are currently taking an aromatase inhibitor (a hormone therapy pill) and have moderate to severe joint or muscle pain from it.
- You have been on the aromatase inhibitor for more than a month and plan to continue for at least a year.
- You are not taking steroids or strong opioid painkillers, and you do not have other serious conditions like heart disease or diabetes.
- You have not had surgery or a fracture near the painful joint in the past 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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