Behavior therapy for reflux symptoms tied to stress responses
Part of Digestive system clinical trials.
This study tests a behavioral approach for people with GERD whose reflux symptoms keep coming back even after they tried an acid-blocking medicine (a PPI). It aims to help by targeting stress-related body responses that may worsen symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You can understand and sign consent, and speak fluent English
- You have ongoing GERD symptoms like heartburn, regurgitation, or non-heart-related chest pain
- You tried a proper PPI (acid blocker) but symptoms still persist, with a GERD questionnaire score of 6 or higher
- You can do required stomach/esophagus tests (endoscopy, 24-hour reflux monitoring, and manometry)
- You are willing to try behavioral (mind/body or lifestyle-based) interventions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at the “upward reflux” that can irritate the throat and sometimes worsen symptoms like cough or asthma. It aims to understand the mechanisms that prevent or allow throat reflux, which may lead to better ways to manage symptoms.
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
This study compares two ways of placing a reflux testing probe to find which works better for women and people with a lower body mass index. You may be able to join if you have typical heartburn or regurgitation symptoms and have not had stomach or esophagus surgery.
This study tests a comprehensive program that combines diet and lifestyle changes to help people with chronic acid reflux (heartburn, acid regurgitation, or chest pain) feel better. It looks at how these changes can improve your overall health and reduce symptoms.
This study looks at how following specific diet and behavior changes affects symptoms of acid reflux (heartburn/regurgitation) in everyday life. It may help you understand what lifestyle steps improve reflux and how symptoms change over time.
This trial tests if a cognitive-behavioral therapy (a type of talk therapy that helps change thoughts and habits) can improve chronic throat and chest symptoms like heartburn, reflux, lump in throat, or trouble swallowing. It is for people who have these symptoms without a known structural problem in the esophagus.
Hear when a new Gastroesophageal Reflux trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.