Check infection prevention in high-risk tibia fractures using a special nail
Part of Injuries & trauma clinical trials.
This study follows people age 18+ who broke the tibia (shin bone) and are at higher risk for infection. It compares a standard internal metal nail to a special coated nail to see which one lowers infection problems and supports healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and can give study consent (or consent rules are met for your type of study participation).
- Your injury is a primary tibia (shin bone) fracture treated with an internal metal nail placed inside the bone (intramedullary nailing).
- Your fracture is considered high risk for infection, such as an open fracture (except certain severe types), delayed treatment after temporary fixation, compartment syndrome needing release surgery, or severe closed tissue injury (specific grades).
- If you join the coated-nail group, you must receive the ZNN Bactiguard tibia nail; if in the control group, you had an uncoated conventional titanium nail.
- You are not pregnant or breastfeeding, and you can attend required follow-up visits and follow the study plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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