Calcium and antibiotic placed inside tibia nail for open fractures
Treatments studied
Part of Injuries & trauma clinical trials.
This Phase 3 study tests whether a calcium/antibiotic “depot” released from an intramedullary nail can lower infection risk in certain open tibia fractures. It may help by delivering antibiotics right at the fracture area while the nail fixes the bone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your leg injury is an open tibia fracture (the wound is open to the outside) and it is Type II or Type III.
- Your fracture is planned to be fixed with an intramedullary nail (a rod placed inside the bone).
- You are not allergic to vancomycin or tobramycin (antibiotics).
- You do not have high blood calcium (hypercalcemia).
- You can speak English or Spanish, and you can be reached by email or phone (or another contact method).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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