Radiation with nedaplatin vs cisplatin for head and neck cancer
Treatments studied
Part of Cancer, Ear, nose & throat clinical trials.
This trial studies whether adding nedaplatin to radiation (with cisplatin as a comparison) can improve treatment for locally advanced head and neck squamous cell carcinoma. It may help people whose tumors cannot be fully removed by surgery or who have higher-risk features after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your legal representative) can sign a written informed consent form
- You are age 18–70 and have confirmed squamous cell carcinoma in the head or neck
- Your cancer is locally advanced and either cannot be treated with surgery or has high-risk surgical features
- Blood tests are within required ranges (enough blood cells, platelets, and neutrophils) and your kidneys and liver work well enough
- You have no recent head-and-neck chemotherapy or radiation in the past 3 months
- You are not pregnant or breastfeeding, and if you could become pregnant you agree to reliable birth control during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two cisplatin dosing schedules (weekly low-dose vs higher dose less often) given alongside radiation for certain head and neck cancers. It’s testing which schedule works well while keeping side effects manageable during planned, curative-intent radiation.
This trial compares two chemotherapy drugs—nedaplatin versus cisplatin—in people newly diagnosed with a specific type of nasopharyngeal cancer. The goal is to see which drug works better and/or has a safer side-effect profile when given as part of standard treatment.
This trial tests whether giving two rounds of cisplatin chemo along with radiation after surgery can help people with high-risk head and neck squamous cell carcinoma. It is for patients who have already had surgery and whose cancer showed signs of being more aggressive.
This trial studies whether adding cisplatin (a chemotherapy medicine) to radiation therapy helps people with stage III–IVA squamous cell cancer of the head and neck after they’ve had surgery. It’s meant to lower the risk of the cancer coming back.
This trial tests whether adding chemotherapy to radiation therapy after surgery can help prevent head and neck cancer from coming back. It is for people who have certain risk factors after their surgery but no signs of cancer spread.
This study tests an optimized plan for treating squamous cell cancer in the head and neck area using curative treatment that includes chemotherapy with cisplatin plus radiation after surgery. It may help doctors improve early management and outcomes for people eligible for this standard approach.
Hear when a new Head and Neck Squamous Carcinoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.