Hemoperfusion for severe sepsis causing multiple organ failure
Treatments studied
Part of Infections clinical trials.
This study tests whether a blood-filter treatment called hemoperfusion can help critically ill people with sepsis that is not responding to standard shock treatment and is affecting multiple organs. It aims to improve recovery when infections are controlled and inflammation markers are very high.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be diagnosed with sepsis, and septic shock treatments have not worked well enough
- The infection source must be in the abdomen, with the infection focus controlled
- You need a medication called noradrenaline (norepinephrine) at over 0.5 micrograms per kilogram per minute despite fluids
- You must have poor function in two or more organs, with a high SOFA score (score about 9 or more)
- Blood tests must show very high inflammation levels (lactate, procalcitonin, CRP, and IL-6)
- You must be age 18 to 80, not pregnant or breastfeeding, not expected to live less than 48 hours, and not on another hemoperfusion device
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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