Cleaning the blood for liver failure with sepsis
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial tests if a special blood-filtering method combined with plasma exchange can help people with severe liver failure and sepsis. It aims to reduce inflammation and improve survival.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have chronic liver disease (with or without cirrhosis).
- Your bilirubin level is very high (over 12 mg/dL).
- Your blood clotting time (INR) is 1.5 or higher.
- You have been diagnosed with sepsis (a severe infection) within the last 72 hours.
- You have high inflammation levels (IL-6 over 80 pg/mL).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a blood-filter treatment called hemoperfusion can help critically ill people with sepsis that is not responding to standard shock treatment and is affecting multiple organs. It aims to improve recovery when infections are controlled and inflammation markers are very high.
This trial tests a device called CytoSorb that filters the blood to reduce inflammation in patients with sudden worsening of chronic liver disease. It may help support organ function and recovery.
This trial tests whether a treatment called plasma exchange (which removes harmful substances from your blood and replaces them with healthy plasma) can help improve the function of other organs, like the kidneys or lungs, in people with advanced liver failure. It aims to find out if this treatment helps you recover better and to identify markers that show if the treatment is working.
This trial looks at whether a blood-filter treatment (called “AN69ST Verse PS” using a hemofilter) can help children with early, serious sepsis and poor circulation or organ problems. It may help stabilize the body faster, but eligibility is limited to certain sepsis situations and recent timing.
This trial tests a blood-filtering treatment for people in septic shock, a severe reaction to infection. It aims to see if removing harmful substances from the blood can help recovery.
This study tests a blood-cleaning treatment to remove harmful toxins from the blood of people with severe abdominal infections. It might help their organs recover faster.
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