Cleaning the blood for liver failure with sepsis
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial tests if a special blood-filtering method combined with plasma exchange can help people with severe liver failure and sepsis. It aims to reduce inflammation and improve survival.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have chronic liver disease (with or without cirrhosis).
- Your bilirubin level is very high (over 12 mg/dL).
- Your blood clotting time (INR) is 1.5 or higher.
- You have been diagnosed with sepsis (a severe infection) within the last 72 hours.
- You have high inflammation levels (IL-6 over 80 pg/mL).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a device called CytoSorb that filters the blood to reduce inflammation in patients with sudden worsening of chronic liver disease. It may help support organ function and recovery.
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This trial studies a blood-cleaning treatment in children with early, serious sepsis to see if it helps organs recover. It’s meant for children who are very sick soon after sepsis starts.
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