Testing a new mitral valve treatment delivered through a catheter
Part of Heart & circulation clinical trials.
This trial tests a new mitral valve device that may improve blood flow in people with significant mitral valve leakage or narrowing, using a catheter instead of open-heart surgery. It’s meant for patients who doctors think this catheter approach is a better fit than surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have mitral valve disease causing either strong leakage (mitral regurgitation grade III or higher) and/or severe narrowing (mitral valve area 1.5 cm² or less).
- Your heart pumping strength (left ventricle ejection fraction, or LVEF) is 30% or higher.
- Your heart team believes a catheter-based valve treatment is more appropriate than open-heart surgery for you.
- You have not had prior valve or related procedures that could interfere with placing the new valve or its function.
- You do not currently need an emergency or urgent heart surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests the Cephea valve, a less invasive option for people with severe mitral valve leakage or narrowing who are not good candidates for open-heart surgery. It checks if the device can safely improve valve function.
This study tracks people with mitral valve disease who receive the Cephea valve through a tube in an artery rather than open-heart surgery. It looks at how well the valve works over time.
This study tests a new catheter-based system to treat severe mitral valve leaking when open-heart surgery is considered high risk. It may help improve blood flow and symptoms by repairing the valve without open surgery, using ultrasound guidance and follow-up visits to track safety and results.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This study looks at how safe and effective a specific catheter procedure is for people with moderate-to-severe mitral valve leakage. It may help those who are considered high risk for traditional open-heart surgery.
This study looks at how long a new mitral valve treatment/device can stay working in people with moderate-to-severe or severe mitral valve leak. It may help avoid or delay surgery for people considered higher risk for mitral valve repair.
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