How radiotherapy changes a tumor’s immune response
Part of Cancer clinical trials.
This study looks at how a tumor’s immune system responds when you receive radiotherapy. It involves taking a planned pre-treatment biopsy so researchers can study immune and tumor changes and see if radiotherapy affects them.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cancer confirmed by pathology, and it’s stage I to IV (cervical, rectal, head and neck, certain lymphomas, or nodal non-Hodgkin lymphoma)
- You can have a biopsy taken from the tumor area that will be within the radiation field before treatment starts
- The biopsy must meet study lab rules (properly fixed in a lab for a set time and enough tumor tissue for testing)
- You’re at least 18 years old, and your overall health score is usually ECOG 0–2 (or ECOG 3 only in a specific situation)
- Your cancer team believes radiotherapy is appropriate for you
- You can sign written consent before joining
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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