Plasma exchange for ICU patients with severe septic shock
Part of Infections clinical trials.
This study tests whether therapeutic plasma exchange (a procedure that removes and replaces blood plasma) can improve outcomes in ICU patients with septic shock that is not responding to standard medicines. It may help some people whose infection-related illness is causing failing organs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be at least 16 years old
- Be in an ICU and have septic shock with low blood pressure despite fluids
- Need ongoing blood pressure medicines (vasopressors) at the time you join
- Start plasma exchange within 48 hours after starting vasopressors
- Have at least one other sign of new organ problems (kidney, breathing, blood counts, or blood chemistry)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether adding plasma exchange (a blood-cleaning treatment) to usual care can improve outcomes for people with new septic shock. If you qualify, you may receive this treatment soon after septic shock is diagnosed to help your body recover.
This trial tests a special blood-filtering method (adaptive blood purification) for people with septic shock caused by a severe infection. It aims to see if this treatment can help control inflammation and improve recovery in the ICU.
This trial tests a blood-filtering device (CytoSorb) that may help control the overwhelming immune response and improve blood vessel function in people with severe septic shock. It's for patients who need strong medications to keep their blood pressure up and who haven't improved with standard care.
This study tests a blood-filtering treatment for people with septic shock, a severe infection that causes very low blood pressure. The treatment aims to remove harmful substances from the blood to help patients recover.
This study tests a new way to give fluids during sepsis in children to improve blood flow and recovery. It compares a standard saltwater solution to a plasma-based solution to see which works better.
This trial looks at how the immune system changes after septic shock in adults in the ICU. It may help doctors better predict or manage complications by studying blood markers a few days after starting treatment.
Hear when a new Septic Shock trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.