Clinical trials
Septic Shock clinical trials
Below are recruiting septic shock clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07774962Recruiting
Comparing fingertip refill time and blood oxygen use in septic shock
This study looks at two ways to check blood flow and oxygen use in people with septic shock, a severe infection-related condition. It aims to see if a simple bedside test (fingertip refill) and a blood measure (oxygen extraction ratio) agree, which could help guide treatment.
IstanbulAges 18 years+ - NCT05148286RecruitingPhase 4
Testing albumin vs fluids for septic shock in the ER
This trial tests whether giving albumin instead of standard crystalloid fluids helps adults with septic shock. It may improve how well your body circulates blood and reduces strain on organs.
SeoulAges 18 years+ - NCT03401398RecruitingPhase 3
Hydrocortisone for children with septic shock in the ICU
This Phase 3 trial tests whether giving stress-dose hydrocortisone can improve outcomes for children with septic shock in the pediatric intensive care unit (PICU). It is designed for children who are already receiving strong medicines to support blood pressure because of a serious infection.
Tucson, ArizonaAges 1 month–17 years - NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT04494074Recruiting
Cooling fever in ventilated people with septic shock
This study tests whether external cooling can safely lower very high fever in people who are on a breathing machine for septic shock. It may help improve outcomes by controlling fever while they are treated for the infection causing their illness.
AmiensAges 18 years+ - NCT04748796RecruitingPhase 3
Landiolol to prevent death in ventilated septic shock patients
This trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can reduce deaths compared with standard care in people in septic shock who have a fast heart rate and strong heart pumping. It is meant for a very specific type of critically ill patient while they are on a breathing machine.
AmiensAges 18 years+ - NCT05726825Recruiting
Add-on plasma exchange for new septic shock
This study tests whether adding plasma exchange (a blood-cleaning treatment) to usual care can improve outcomes for people with new septic shock. If you qualify, you may receive this treatment soon after septic shock is diagnosed to help your body recover.
InnsbruckAges 18–80 - NCT05969275RecruitingPhase 2
Cell therapy trial for infection-related septic shock in ICU
This Phase 2 trial tests an immune-boosting cell therapy (umbilical mesenchymal stromal cells) in people with septic shock—when infection causes dangerous stress on the heart and other organs. The goal is to see if this treatment can improve outcomes compared with standard care.
Ottawa, OntarioAges 18 years+ - NCT06225258RecruitingPhase 2
Hops compound for septic shock treatment
This trial tests whether a natural compound from hops (xanthohumol) can help people with severe septic shock. It's given early, within the first day, alongside standard intensive care.
Lublin, Lublin VoivodeshipAges 18 years+ - NCT06234592Recruiting
Blood pressure medicines and kidney health in septic shock
This trial tests whether different blood pressure medicines protect kidney function better in people with septic shock (a severe infection that causes low blood pressure). It compares norepinephrine (the standard treatment) with other options to see which is best for the kidneys.
LondonAges 18 years+ - NCT06481410Recruiting
Methylene blue for severe septic shock
This trial is testing whether a medication called methylene blue can help people with severe septic shock who are already on strong blood pressure support (norepinephrine). The goal is to see if it improves survival and reduces the need for other treatments.
Hangzhou, ZhejiangAges Any age - NCT06499467Recruiting
Comparing second blood pressure medicines for septic shock
This trial tests different combinations of blood pressure medicines given to patients on a breathing machine who have septic shock. The goal is to find the best dose of a second medicine when norepinephrine alone isn't enough.
Lucknow, Uttar PradeshAges 18–80 - NCT06786364Recruiting
Measuring blood flow waves in sepsis patients
This study uses a special light sensor to measure blood flow waves in patients with septic shock. The goal is to see if these waves can help doctors understand how severe the shock is.
Mexico City, CuauhtemocAges 18 years+ - NCT06809868Recruiting
Study of genetic elements in sepsis and aging
This trial looks at how certain genetic elements may affect the immune system in older adults with sepsis. It aims to understand why older patients may respond differently to severe infections.
San Francisco, CaliforniaAges 18 years+ - NCT06832436Recruiting
Atrial strain study in septic shock patients
This study looks at how well the upper chambers of the heart (atria) work during septic shock using a special heart ultrasound. It may help doctors understand how the heart is affected by severe infections.
SalouëlAges 18 years+ - NCT06853340Recruiting
Calcium and blood vessel hardening in sepsis shock
This study looks at how calcium buildup in blood vessels and a specific receptor on immune cells might affect recovery from septic shock. It aims to understand if these factors impact how well patients respond to treatment.
AmiensAges 18 years+ - NCT06990295Recruiting
Ultrasound spleen stimulation for sepsis shock
This trial tests if using focused ultrasound to stimulate the spleen can reduce inflammation in septic shock. It may help patients in the ICU who need strong blood pressure support.
Wuhu, AnhuiAges 18 years+ - NCT07096284Recruiting
Study of a blood oxygen ratio in septic shock
This trial tests a new way to measure oxygen levels in the blood of patients with septic shock. It may help doctors better understand how well the body is using oxygen.
Marrakesh, MarrakeshAges 18 years+ - NCT07203833Recruiting
Vasorin test for shock diagnosis and outlook
This study looks at a protein called vasorin in the blood to see if it can help diagnose and predict outcomes in people with severe shock in the ICU. It compares patients with septic shock (caused by infection) to those with shock from other causes.
AmiensAges 18 years+ - NCT07273526Recruiting
Adrenaline vs. Dopamine for septic shock in children
This study compares two medicines, adrenaline and dopamine, to see which works better for children with septic shock (a serious infection causing very low blood pressure) that does not improve with fluids.
Faisalābad, Punjab ProvinceAges 1 month–1 year - NCT07383103RecruitingPhase 4
Steroid combination for septic shock
This trial tests whether two medicines (hydrocortisone and fludrocortisone) can help people with severe infections that cause dangerously low blood pressure (septic shock). It's for patients who have just been diagnosed and haven't used steroids recently.
Yangzhou, JiangsuAges 18–90 - NCT07451886RecruitingPhase 2
Fludrocortisone for septic shock
This study tests whether adding a steroid called fludrocortisone to standard care helps people with septic shock (a dangerous drop in blood pressure from infection) get better faster. If you are in the ICU, on a breathing machine, and need strong medication for your blood pressure, you may be eligible.
Hong KongAges 18 years+ - NCT07616817Enrolling by invitation
Expert Panel Study on Ultrasound Assessment of Septic Shock
This study gathers expert opinions from critical care doctors and specialists around the world who use bedside ultrasound (a portable imaging tool) to diagnose and categorize septic shock (a life-threatening infection condition). The goal is to develop standardized approaches to identifying different types of septic shock using ultrasound.
Albany, New YorkAges Any age - NCT06692036Enrolling by invitation
Blood filtering for septic shock
This trial tests a special blood-filtering method (adaptive blood purification) for people with septic shock caused by a severe infection. It aims to see if this treatment can help control inflammation and improve recovery in the ICU.
Beijing, Beijing MunicipalityAges 18–82
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Septic Shock trials by city
Studies with a site in or near these metro areas.
Septic Shock trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for septic shock?
- Yes. Clin2 currently lists 120 recruiting septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.