Blood filter treatment for septic shock
Part of Heart & circulation, Infections clinical trials.
This trial tests a blood-filtering device (CytoSorb) that may help control the overwhelming immune response and improve blood vessel function in people with severe septic shock. It's for patients who need strong medications to keep their blood pressure up and who haven't improved with standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have septic shock and need strong blood pressure medication (more than 0.5 µg/kg/min of norepinephrine or similar).
- Your blood lactate level is between 2 and 8 mmol/L at the start of the study.
- You are still experiencing signs of poor blood flow (like high lactate or slow capillary refill) despite standard treatment.
- You must be on a corticosteroid for at least 30 minutes before starting.
- You must have certain monitoring devices already in place (arterial line, central line, and a PiCCO device).
- You must be enrolled within 12 hours of first needing vasopressors, and other causes of shock (like heart or blockage problems) must be ruled out.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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