Study of children’s heart disease caused by MYBPC3 gene changes
Part of Genetic & congenital, Heart & circulation clinical trials.
This is an observational study that follows children under 18 with cardiomyopathy caused by certain MYBPC3 gene mutations. It aims to better understand how the disease changes over time, which may help future treatments be better targeted.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are under 18 years old (or the data is from when the patient was under 18)
- Genetic testing shows a pathogenic or likely pathogenic MYBPC3 mutation
- For the prospective part: you have cardiomyopathy (HCM, DCM, RCM, mixed types, or LVNC)
- If you are a MYBPC3 “infant” type case (homozygous or compound heterozygous), you may be eligible even in early life
- You have not had a heart transplant (or the study data must fit the study’s timing rules)
- You are not in another interventional (treatment) trial at the same time, unless the sponsor allows it
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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