Antibiotic plan study for ventilator pneumonia in ICU
Part of Infections, Lungs & breathing clinical trials.
This trial tests an “antibiotic stewardship” approach—choosing and adjusting antibiotics in a smarter way—for a first episode of pneumonia in patients on a breathing machine. It may help ensure the right antibiotics are used at the right time, while avoiding unnecessary or overly broad treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have your first confirmed ventilator-associated pneumonia (VAP) with positive lab testing
- You must be on a breathing machine for more than 48 hours when the sample is taken
- You must have signs of infection and worsening breathing/oxygen levels right before the first antibiotic dose
- You must start an appropriate antibiotic plan around the time of diagnosis (even if initially “best guess”)
- You (or your legal representative) must be able to give consent, including via an emergency process if needed
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
This study watches patients in the intensive care unit (ICU) who are on a breathing machine (ventilator) to learn more about pneumonia that can happen from the machine. The goal is to understand how to better prevent and treat this infection.
This trial looks at how well doctors followed current guidelines to diagnose ventilator-associated pneumonia (a lung infection from a breathing tube) in ICU patients between 2022 and 2024. It aims to improve future care.
This study looks at how well antibiotics work for pneumonia caused by a specific bacterium (Stenotrophomonas maltophilia) in patients who are on breathing machines in the intensive care unit (ICU). It will help doctors choose the best treatment.
This trial tests whether breathing in special viruses (called phages) that attack the Pseudomonas bacteria can help clear a serious lung infection in patients on ventilators. The treatment is added to standard antibiotics and may help fight the infection better.
This study tests whether using a DNA test on lung fluid can help doctors choose better antibiotics for pneumonia in ICU patients with weakened immune systems. It may lead to more effective treatment and fewer side effects.
Hear when a new Ventilator Associated Pneumonia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.