Study of a new heart valve for severe aortic stenosis
Part of Heart & circulation clinical trials.
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe narrowing of your aortic heart valve (aortic stenosis) that is caused by calcium buildup.
- Your aortic valve opening is the right size for the new valve.
- You have symptoms like fatigue, shortness of breath, or chest pain (NYHA class II or higher).
- You are able to have the valve placed through a blood vessel in your leg.
- You have not had a heart valve replacement before and do not need another heart valve repair soon.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a new “valve-in-valve” procedure to treat a failing aortic bioprosthetic valve. It may help people improve blood flow through the heart valve and reduce valve-related problems.
This trial studies whether a new transcatheter aortic valve (SAPIEN X4) is safe and works well in people whose previously implanted aortic valve is now failing. It may help reduce valve symptoms in higher-surgery-risk patients who are not good candidates for open-heart valve replacement.
This trial tests a new, less invasive heart valve (called SAPIEN X4) placed through a vein in your leg to replace a failing mitral valve that was previously repaired or replaced. It is for people who are at high risk for open-heart surgery and have a leaky or narrowed mitral valve.
This trial tests a new heart valve device (Venus-Vitae) for people with severe aortic stenosis, a condition where the heart valve is too tight. It aims to see if the device works well for patients of all surgical risk levels.
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
This study compares a new artificial aortic valve (Myval THV) with standard medical treatment for people with moderate aortic stenosis—a condition where the heart valve doesn't open fully. The trial tests whether the new valve can help improve symptoms and heart function.
Hear when a new Aortic Stenosis, Severe trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.