Cryotherapy treatment for painful, hard-to-remove NF1 tumors
Part of Brain & nervous system, Cancer clinical trials.
This trial tests whether freezing treatment done through the skin (cryotherapy) can reduce pain and discomfort from certain non-cancer NF1 tumors that can’t be safely removed. You may be able to join if you’re an adult with NF1, a painful or bothersome benign lesion, and can safely undergo procedures like MRI.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have neurofibromatosis type 1 (NF1) as defined by standard medical criteria.
- You need a benign (not cancerous) neurofibroma that is painful and/or causes functional discomfort, and cannot be removed safely (or removal would cause unacceptable scarring).
- Your recent blood test should show neutrophils above 1 G/L within the last 14 days, and your blood clotting tests should be acceptable.
- You must not be on chemotherapy or targeted anti-cancer medicines during the trial.
- You need to be able to safely have MRI scans and a skin freezing procedure; also pregnancy and breastfeeding aren’t allowed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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