Clin2
NCT05229341Possibly a fitRecruiting

Testing DNA “methylation” to evaluate thyroid nodule samples

Thyroid Gland Carcinoma

Part of Cancer, Hormones & metabolism clinical trials.

This study looks at patient tissue from needle biopsies to see if DNA “methylation” patterns can help diagnose and guide treatment for thyroid nodules. You might benefit by helping improve how these nodules are evaluated, using information from your biopsy sample and medical data.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,450 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You are scheduled to get a needle biopsy to check a thyroid nodule
  • You can make your own medical decisions (or otherwise do not lack decision-making ability)
  • You are willing to sign informed consent so your tissue and medical information can be used
  • This study is only for adults; children cannot join

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04742608Recruiting
Liquid blood tests to diagnose thyroid nodules or cancer

This study tests whether a blood “liquid biopsy” can help diagnose thyroid cancer or hard-to-tell thyroid nodules without needing extra procedures. It may help confirm what’s going on before or around planned thyroid surgery.

Los Angeles, California
NCT06207188Recruiting
Using sound waves to tell thyroid lumps apart

This study uses a special ultrasound technique to look at thyroid nodules and lumps in the neck. The goal is to tell the difference between harmless lumps and cancer, so you may get a clearer answer without extra procedures.

Scottsdale, Arizona
NCT03676647Recruiting
Test DNA methylation from thyroid FNA samples to diagnose cancer

This study looks at a molecular test (DNA methylation pattern) using samples taken during fine-needle aspiration (FNA) of thyroid nodules. It aims to help identify which thyroid nodules that looked “unclear” after the first test may be cancer.

Duarte, California
NCT06220656Recruiting
Thyroid nodule observation and biopsy study

This study looks at how doctors talk with patients who have a thyroid nodule that may need a biopsy. It aims to improve communication and help patients feel more involved in their care.

Lebanon, New Hampshire
NCT07041307Recruiting
Study of blood flow in thyroid nodules before surgery

This trial uses a special imaging technique to look at the tiny blood vessels inside thyroid nodules before they are removed. It may help doctors understand which nodules are cancerous.

Copenhagen
NCT05837260Recruiting
Tracking tumor DNA changes in advanced thyroid cancers

This study looks at a small blood test (called ctDNA) and tumor tissue to understand how advanced thyroid cancers change over time. It may help doctors better monitor cancer growth and guide treatment choices.

London

Hear when a new Thyroid Gland Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.