Surgery choice for lung spread of osteosarcoma
Part of Cancer clinical trials.
This Phase 3 trial compares two ways to remove lung metastases (open surgery vs keyhole surgery) in people with osteosarcoma. It aims to see which approach works better and is safer for patients with a limited number of lung spots that can be removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are under 50 years old when you join the study.
- You have osteosarcoma confirmed by tissue biopsy (not just suspected).
- Your lung spread looks like 1–4 nodules, each small enough to be removed (and at least one is at least 3 mm).
- The lung nodules can be removed with either open chest surgery (thoracotomy) or keyhole surgery (thoracoscopic) as judged by the surgeon.
- You have no spread outside the lungs (no extrapulmonary metastases), at least based on your workup before enrollment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether combining an immunotherapy drug (atezolizumab) with focused radiation and surgery can help people whose osteosarcoma has come back only in the lungs. It aims to see if this approach is safe and may improve outcomes.
This trial tests a combination of immunotherapy and targeted radiation before surgery for osteosarcoma that has spread to the lungs. It aims to see if this approach can help shrink or control the lung tumors and make surgery more effective.
This trial tests removing the tumor with surgery first, then following up with chemotherapy. It's for people with a new, high-grade osteosarcoma in an arm or leg that hasn't spread.
This trial tests a special dye that targets B7-H3, a protein found on osteosarcoma cells. Before your surgery, the dye is injected and helps surgeons see tumor edges more clearly, so they can remove all of the cancer while saving healthy tissue.
This trial tests a single, high-dose internal radiation treatment (brachytherapy) for large osteosarcoma tumors that can't be removed by surgery and haven't responded to other treatments. It may offer a new option for shrinking these difficult-to-treat masses.
This trial tests a new targeted radiation treatment (177Lu-TARGETed Osteosarcoma Therapy) for people with advanced osteosarcoma that has not responded to or has come back after prior chemotherapy. The goal is to see if this treatment can help shrink or control the cancer.
Hear when a new Metastatic Malignant Neoplasm in the Lung trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.