Stool transplant to treat early C. difficile infection
Treatments studied
Part of Infections clinical trials.
This trial tests whether giving a stool transplant (also called FMT) can treat a new, early C. difficile infection in people who have improved while on antibiotics. It may help some people prevent the infection from coming back or worsening.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are older than 18 years
- Your stool test for C. difficile PCR is positive and you have symptoms like diarrhea/enteritis
- Your diarrhea fully went away during the antibiotics used to treat this C. difficile infection
- You are not taking any other antibiotics now and not taking probiotics now
- You can sign consent (for example, you are not unable to consent due to dementia)
- You can hold the enema safely (no severe fecal incontinence)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a freeze-dried fecal microbiota transplant (FMT) to see if it helps with diarrhea-predominant irritable bowel syndrome (IBS-D) or prevents repeat C. diff infections. FMT introduces healthy bacteria into your gut to restore balance.
This study is looking at people who were treated for C. diff (a serious gut infection) at Umeå University Hospital to see how they are doing years later. It compares people who got a fecal transplant (a treatment that restores healthy gut bacteria) with those who only took antibiotics.
This trial tests whether a stool transplant (fecal microbiota transplantation) can help manage active ulcerative colitis. You would receive a transplant from a healthy donor to see if it improves your symptoms.
This study looks at “rescue” fecal microbiota transplantation (FMT), which replaces gut microbes using stool from a screened donor, for intestinal infections that have not improved with standard care. It may help patients whose infection keeps coming back or doesn’t respond to treatment.
This study tests whether taking a capsule form of fecal microbiota transplant (FMT) can help adults with their first C. difficile infection—or a first relapse—get better and reduce repeat episodes. Participants also take specific antibiotics for C. difficile as part of the study process.
This trial compares three treatments for a severe diarrhea infection called C. diff: a fecal transplant (putting healthy donor stool into your gut), a newer antibiotic called fidaxomicin, and an older antibiotic called vancomycin. The goal is to see which works best and prevents the infection from coming back.
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