Clin2
NCT05269628Possibly a fitRecruiting

Cannabidiol for multiple sclerosis sleep and pain patterns

Multiple SclerosisSleepPain

Treatments studied

Part of Brain & nervous system, Immune system & allergy, Pain clinical trials.

This study looks at whether cannabidiol (CBD, a cannabis-related medicine) can improve symptoms in people with multiple sclerosis (MS), especially how sleep and pain type affect outcomes. It’s mainly for people with MS and ongoing moderate-to-severe pain, while carefully checking safety and medication interactions.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
166 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You have clinically definite multiple sclerosis and can stay on your current MS treatment without dose changes for at least 3 months
  • You have pain that lasts at least 3 months and is moderate to severe (rated 4–10 out of 10)
  • You can keep your pain medicines at the same doses during the study
  • You had recent liver blood tests (AST, ALT, bilirubin) within the last 90 days that are acceptable
  • You can’t have certain sleep disorders (like shift-work sleep disorder or narcolepsy confirmed by sleep tests)
  • You must not use cannabinoid products (including CBD/THC) for 30 days before and during the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06266611Recruiting· Phase 2
Cannabis for cancer symptom relief

This trial tests whether cannabis can help cancer patients manage symptoms like sleep trouble, pain, and mood changes. It's for people who are new to using cannabis for these issues.

Aurora, Colorado
NCT06261489Recruiting· Phase 2
Cannabis for bladder problems in multiple sclerosis

This study tests whether cannabis, with either THC or CBD, helps with bladder and urinary symptoms caused by multiple sclerosis. It compares two types of cannabis to see which works better.

Calgary, Alberta
NCT07527338Not yet recruiting· Phase 2
Cannabidiol for sleep problems in people who drink alcohol

This study tests whether a daily capsule of cannabidiol (CBD), a compound from cannabis, can improve sleep quality in people who drink alcohol at risky levels and have poor sleep. It aims to see if CBD helps you sleep better and may also reduce alcohol-related harm.

NCT05092191Recruiting· Phase 2
Cannabis pill study for MS-related muscle stiffness

This Phase 2 trial tests whether cannabis can reduce muscle stiffness (spasticity) in people with multiple sclerosis. You may be able to participate if your stiffness is not improving with your current treatments.

Montreal, Quebec
NCT04526093Recruiting
Study of medical cannabis using patient symptom reports

This study looks at how medical cannabis affects symptoms like pain, epilepsy, sleep, and anxiety or depression, based on what patients report over time. It may help researchers understand what works in real life when people use verified medical cannabis products.

Toronto, Ontario
NCT06290063Recruiting· Phase 2
CBD for older adults who use cannabis

This study tests whether a pure CBD product (Epidiolex) can help older adults who use cannabis occasionally. It looks at how CBD affects people who already take medications for pain, sleep, or mood issues.

Boulder, Colorado

Hear when a new Multiple sclerosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.