Clin2
NCT05295433Possibly a fitRecruiting

Long-term follow-up for an mRNA vaccine dose you already received

Methylmalonic Acidemia

Part of Genetic & congenital, Hormones & metabolism clinical trials.

This is a follow-up study that checks the long-term safety and health benefits of mRNA-3705 for people who took it in an earlier trial (or had to pause dosing due to COVID-19 vaccination). You may be invited if you completed the earlier study schedule or can transition early because you missed several doses.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
56 people
Ages
1 year and older
Study type
Interventional

Who can take part

  • You previously took mRNA-3705 in another mRNA-3705 study (or you can switch early after missing more than 3 doses because of COVID-19 vaccination).
  • You finished your last study checkup (end-of-treatment/end-of-study visit) within 10 days before starting this extension.
  • Your study doctor thinks you are likely to benefit from continuing mRNA-3705.
  • You don’t have any new health issue (lab abnormality or medical condition) that could make the study riskier for you.
  • You have not had a liver or kidney transplant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05130437Recruiting· Phase 1/Phase 2
Follow-up study for an mRNA vaccine given before

This is a follow-up study for people who already received the mRNA-3927 vaccine in an earlier trial. It looks at how safe the treatment is over the long term and whether it continues to have benefit.

Los Angeles, California
NCT06810934Recruiting· Phase 1/Phase 2
New COVID-19 vaccine study for those with prior mRNA vaccines

This study tests a new type of COVID-19 vaccine that is designed to train your immune system to make stronger, longer-lasting protection. You may be able to join if you are 40–64, have already had at least two doses of a mRNA COVID-19 vaccine (Pfizer or Moderna) more than 4 months ago, and are generally healthy.

Los Angeles, California
NCT04159103Recruiting· Phase 1/Phase 2
mRNA treatment for propionic acidemia, tested in a study

This trial tests an mRNA medicine (mRNA-3927) in people with propionic acidemia (PA). It aims to see whether this treatment is safe and can help the body when PA is confirmed by genetic testing.

Los Angeles, California
NCT04064060Recruiting· Phase 3
Long-term safety follow-up for luspatercept study participants

This trial studies the long-term safety of luspatercept (ACE-536) in people who already took part in an earlier luspatercept study. It mainly helps doctors better understand ongoing side effects and overall safety over time.

Los Angeles, California
NCT05768386Enrolling by invitation
Long-term follow-up for severe hemophilia A after BMN 270 study

This study checks how people with severe hemophilia A are doing over time after joining a previous BioMarin study of BMN 270. It helps researchers understand long-term safety and outcomes and may support your ongoing care plan.

Los Angeles, California
NCT07544420Not yet recruiting· Phase 1
Testing a New mRNA Therapy in Healthy Adults

This is an early-stage trial testing a new type of treatment called mRNA therapy that helps your body make missing proteins. Researchers are enrolling healthy volunteers to understand how safe and well-tolerated this approach is.

Roatán, Bay Islands

Hear when a new Methylmalonic Acidemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.