Testing LOXO-783 for PIK3CA-mutated cancers
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests an experimental drug (LOXO-783) for people with advanced breast cancer or other solid tumors that have a specific change in the PIK3CA gene. The goal is to see if the drug can shrink or slow the growth of the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your cancer must have a specific change in the PIK3CA gene (called H1047R or another activating mutation).
- You must have a stored tumor sample available from a past procedure, or get approval to join without one.
- You must have finished all previous cancer treatments and recovered from major side effects.
- Your blood tests must show that your organs are working well enough.
- You must be able to take care of yourself (ECOG score 0 or 1) and have at least one tumor that can be measured on scans.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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