Gut bacteria study in toddlers on long-term reflux antibiotics
Part of Infections, Kidney & urinary clinical trials.
This study compares gut bacteria (microbiome) in toddlers who take an antibiotic to prevent urine infections for vesicoureteral reflux, versus other similar children. It may help researchers understand how long-term antibiotic use and reflux affect gut health and future risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child is covered by a health insurance plan
- You (parent/guardian) agree for your child to join
- Your child eats a varied diet (not very limited)
- Your child is in one of these groups: grade 3+ reflux on trimethoprim-sulfamethoxazole for 5+ months, or reflux/urine problems without long-term trimethoprim-sulfamethoxazole, or otherwise healthy without long-term trimethoprim-sulfamethoxazole
- Your child has no ongoing gut disease (like chronic digestive illness or inflammatory bowel disease)
- No recent stomach/intestinal infection or antibiotics that would change gut bacteria (no gastroenteritis/colitis in last 15 days; no curative antibiotics in last month)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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