Effect of PPI treatment on gut bacteria in children
Part of Digestive system clinical trials.
This study looks at how proton pump inhibitors (PPIs), a type of medicine that reduces stomach acid, affect the natural bacteria in the gut of children and teenagers. It may help us understand if PPIs change gut health, which could guide future treatment decisions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 6 months and 17 years old.
- Your doctor has recommended a PPI medicine for conditions like acid reflux, esophagitis (inflammation of the food pipe), or functional dyspepsia (indigestion).
- You must be able to provide stool samples at set times during the study.
- You cannot have taken antibiotics, antifungal medicines, or probiotics (healthy bacteria supplements) within the last 30 days or during the study.
- You cannot have a weak immune system, inflammatory bowel disease (like Crohn's or ulcerative colitis), or celiac disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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