Tested surgery to help immune function in cirrhosis
Part of Digestive system clinical trials.
This study looks at whether a type of keyhole spleen surgery plus cutting a large vein can improve immune function in people with cirrhosis. It may help reduce immune problems that can happen after complications like bleeding from varices (enlarged veins in the esophagus/stomach).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have cirrhosis confirmed by tests (clinical, imaging, or biopsy).
- You have an enlarged spleen with “hypersplenism,” meaning the spleen is overactive.
- You have had bleeding from esophageal or stomach varices (enlarged veins).
- You are able to consent to take part in the study.
- You are not pregnant and can follow the study’s pregnancy rules.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at whether a minimally invasive spleen surgery (with a specific vein-disconnection procedure) can better protect liver function in people with cirrhosis who have had variceal bleeding. It may help reduce stress on the liver after treatment, but you must meet several safety criteria.
This study looks at whether removing the spleen using keyhole surgery can improve “liver reserve function” in people with cirrhosis. It may be considered for patients who have an enlarged spleen and very low platelets, but it also has several safety exclusions.
This study tests whether removing an enlarged spleen through keyhole surgery can improve kidney function in people with cirrhosis and an overactive spleen. The trial follows patients for two years to see if the surgery helps protect the kidneys.
This study is testing a keyhole surgery to remove part of an enlarged spleen in people with cirrhosis. It aims to improve low blood counts and reduce the risk of further bleeding from stomach or esophagus veins.
This study looks at whether removing an enlarged spleen (splenectomy) in people with cirrhosis can improve their blood fat (lipid) levels over two years. It may help those with low blood counts due to an overactive spleen.
This study tests a surgery (LSD) in people with liver cirrhosis who have had bleeding from enlarged veins in the food pipe or stomach. It looks at whether the surgery helps improve blood fat levels over two years, which might lower future risks.
Hear when a new Splenectomy; Status trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.